Blood vessels play a crucial role in the body, delivering oxygen and nutrients to organs and tissues and removing waste products. However, when glucose levels in the bloodstream are chronically high, blood vessels can be damaged in various ways. This damage can lead to a range of complications associated with diabetes, including cardiovascular disease, retinopathy, and kidney damage. In this article, we will explore how high glucose levels can damage blood vessels through processes such as glycation, oxidative stress, and advanced glycation end product (AGE) accumulation. By understanding these mechanisms, we can better appreciate the importance of controlling blood glucose levels to prevent or minimize complications associated with diabetes. The Process of Glycation Glycation is a chemical process that occurs when glucose molecules bind to proteins and lipids in the blood vessel walls. This process is also known as non-enzymatic glycosylation, and it happens naturally in the body to s...
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